Les publications des Arcad group

Grâce à la création des arcad groups et aux travaux effectués sur ses bases de données, la Fondation a permis la publication de nombreux articles dans des journaux de recherche et de médecine internationaux.

2024

LIVERMETSURVEY / Response to neodjuvant therapy-a predictor of early recurrence in colorectal liver metastasis : a LiverMetsurvey study (abstract accepted IHPBA 2024, Manuscript submitted)

COLORECTAL /André T, Raeisi M, Shi Q, Yoshino T, Zalcberg JR, Adams RA, Cremolini C, Grothey A, Mayer RJ, Li J, Chibaudel B, de Gramont A. Prognostic value of liver metastases, KRAS mutations and race in colorectal cancer patients: A pooled analysis of third-line placebo-controlled trials from the ARCAD database. ESMO (Poster). 2024; Abstract no. 531P. DOI: 10.1016/j.annonc.2024.08.600

COLORECTAL / Cohen R, Raeisi M, Chibaudel B, Shi Q, Yoshino T, Zalcberg JR, Adams R, Cremolini C, Van Cutsem E, Heinemann V, Tabernero J, Punt CJA, Arnold D, Hurwitz HI, Douillard JY, Venook AP, Saltz LB, Maughan TS, Kabbinavar F, Bokemeyer C, Grothey A, Mayer RJ, Kaplan R, Tebbutt NC, Randolph Hecht J, Giantonio BJ, Díaz-Rubio E, Sobrero AF, Peeters M, Koopman M, Goldberg RM, Andre T, de Gramont A. Prognostic value of liver metastases in colorectal cancer treated by systemic therapy: An ARCAD pooled analysis. Eur J Cancer. 2024 Jun 10;207:114160. doi: 10.1016/j.ejca.2024.114160.  Disponible sur : https://www.ejcancer.com/article/S0959-8049(24)00816-5/abstract

COLORECTAL / Cohen R, Raeisi M, Chibaudel B, Yoshino T, Shi Q, Zalcberg JR, Adams R, Cremolini C, Grothey A, Mayer RJ, Van Cutsem E, Tabernero J, Bando H, Misumi T, Overman MJ, André T, de Gramont A. Efficacy of immune checkpoint inhibitors for metastatic colorectal cancer with microsatellite instability in second or latter line using synthetic control arms: A non-randomised evaluation. Eur J Cancer. 2024 Mar, 199:113537 DOI: 10.1016/j.ejca.2024.113537
Disponible sur :  https://www.ejcancer.com/article/S0959-8049(24)00013-3/abstract

COLORECTAL / Karapetis CS, Liu H, Sorich MJ, Pederson LD, Van Cutsem E, Maughan T, Douillard JY, O’Callaghan CJ, Jonker D, Bokemeyer C, Sobrero A, Cremolini C, Chibaudel B, Zalcberg J, Adams R, Buyse M, Peeters M, Yoshino T, de Gramont A, Shi Q. Fluoropyrimidine type, patient age, tumour sidedness and mutation status as determinants of benefit in patients with metastatic colorectal cancer treated with EGFR monoclonal antibodies: individual patient data pooled analysis of randomised trials from the ARCAD database. Br J Cancer. 2024 Feb 24, PMID: 38402342 DOI: 10.1038/s41416-024-02604-y
Disponible sur : https://www.nature.com/articles/s41416-024-02604-y 

2023

LIVERMETSURVEY / Colorectal Liver Metastasis Jean-Nicolas Vauthey, Yoshikuni Kawaguchi, René Adam : 549-556 Springer Nature 2023
Disponible sur : https://doi.org/10.1007/978-3-031-09323-4

COLORECTAL / Takeda Y, Misumi T, Bando H, Suzuki M, Wakabayashi M, Oki E, Yamazaki K, Kakeji Y, Shitara K, Terashima M, Raeisi M, Maehara Y, Ohtsu A, Andre T, De Gramont A, Shi Q, Yoshino T. ARCAD-Asia initiative: leveraging yesterday’s data for tomorrow ESMO Gastrointestinal Oncology, Volume 2, 2023, 100007, ISSN 2949-8198
Disponible sur : https://www.esmogastro.org/article/S2949-8198(23)00008-0/fulltext

COLORECTAL / Yoshino T, Shi Q, Misumi T, Bando H, Wakabayashi M, Raeisi M, Andre T, de Gramont A. A synthetic control arm for refractory metastatic colorectal cancer: the no placebo initiative. Nat Med 2023 Oct, 29 (10):2389-2390 PMID: 37507606 DOI: 10.1038/s41591-023-02488-0
Disponible sur : https://www.nature.com/articles/s41591-023-02488-0

COLORECTAL / Ou FS, Ahn DH, Dixon JG, Grothey A, Lou Y, Kasi PM, Hubbard JM, Van Cutsem E, Saltz LB, Schmoll HJ, Goldberg RM, Venook AP, Hoff P, Douillard JY, Hecht JR, Hurwitz H, Punt CJA, Koopman M, Bokemeyer C, Fuchs CS, Diaz-Rubio E, Tebbutt NC, Cremolini C, Kabbinavar FF, Bekaii-Saab T, Chibaudel B, Yoshino T, Zalcberg J, Adams RA, de Gramont A, Shi Q. Evaluation of Intratumoral Response Heterogeneity in Metastatic Colorectal Cancer and Its Impact on Patient Overall Survival: Findings from 10,551 Patients in the ARCAD Database. Cancers (Basel). 2023 Aug 15, 15 (16) PMID: 37627145 PMCID: 10452983 DOI: 10.3390/cancers15164117
Disponible sur : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452983/

COLORECTAL / Margalit O, Harmsen WS, Shacham-Shmueli E, Voss MM, Boursi B, Wagner AD, Cohen R, Olswold CL, Saltz LB, Goldstein DA, Hurwitz H, Tebbutt NC, Kabbinavar FF, Adams RA, Chibaudel B, Grothey A, Yoshino T, Zalcberg J, de Gramont A, Shi Q, Lenz HJ. Evaluating sex as a predictive marker for response to bevacizumab in metastatic colorectal carcinoma: Pooled analysis of 3,369 patients in the ARCAD database. Eur J Cancer. 2023 Jan, 178:162-170 PMID: 36446161 DOI: 10.1016/j.ejca.2022.10.022
Disponible sur : https://www.ejcancer.com/article/S0959-8049(22)01325-9/fulltext

2022

LIVERMETSURVEY / The LiverMetSurvey Registry MA Allard, V Cailliez, B Chibaudel, A de Gramont, R Adam
Disponible sur : https://doi.org/10.1007/978-3-031-09323-4_58

LIVERMETSURVEY / Innominato PF, Cailliez V, Allard MA, Lopez-Ben S, Ferrero A, Marques H, Hubert C, Giuliante F, Pereira F, Cugat E, Mirza DF, Costa-Maia J, Serrablo A, Lapointe R, Dopazo C, Tralhao J, Kaiser G, Chen JS, Garcia-Borobia F, Regimbeau JM, Skipenko O, Lin JK, Laurent C, Opocher E, Goto Y, Chibaudel B, de Gramont A, Adam R. Impact of Preoperative Chemotherapy Features on Patient Outcomes after Hepatectomy for Initially Unresectable Colorectal Cancer Liver Metastases: A LiverMetSurvey Analysis. Cancers (Basel). 2022 Sep 5 ; 14(17):4340
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/36077874/

COLORECTAL / Franko J, Yin J#, Adams RA, Zalcberg J, Fiskum J, Van Cutsem E, Goldberg RM, Hurwitz H, Bokemeyer C, Kabbinavar F, Curtis A, Meyers J, Chibaudel B, Yoshino T, de Gramont A, Shi Q, ARCAD collaborators. Trajectories of body weight change and survival among patients with mCRC treated with systemic therapy: Pooled analysis from the ARCAD database. Eur J Cancer. 2022 Aug 19, 174:142-152 PMID: 35994794 DOI: 10.1016/j.ejca.2022.07.021
Disponible sur : https://www.ejcancer.com/article/S0959-8049(22)00445-2/abstract

COLORECTAL / McCleary NJ, Harmsen WS, Haakenstad E, Cleary JM, Meyerhardt JA, Zalcberg J, Adams R, Grothey A, Sobrero AF, Van Cutsem E, Goldberg RM, Peeters M, Tabernero Seymour M, Saltz LB, Giantonio BJ, Arnold D, Rothenberg ML, Koopman M, Schmoll H-J, Pitot HC, Hoff PM, Tebbutt N, Masi G, Souglakos J, Bokemeyer C, Heinemann V, Yoshino T, Chibaudel B, MD, deGramont A, Qian Shi Q, Lichtman SM, Metastatic Colorectal Cancer Outcomes by Age Among ARCAD First- and Second-Line Clinical Trials,  JNCI Cancer Spectrum, Volume 6, Issue 2, April 2022, pkac014
Disponible sur :  
https://doi.org/10.1093/jncics/pkac014 

COLORECTAL / Papamichael D, Lopes GS, Olswold CL, Douillard J-Y, Adams RA, Maughan RS, Van Cutsem E, Venook AP, Lenz H-J, Heinemann V, Kaplan R, Bokemeyer C, Chibaudel B, Grothey A, Yoshino T, Zalcberg J, De Gramont A, Shi Q. Efficacy of anti-EGFR agents in RAS Wildtype metastatic colorectal cancer patients ≥ 70 years. Eur J Cancer. 2022 Jan 13, 163:1-15 PMID: 35033994 DOI: 10.1016/j.ejca.2021.12.007
Disponible sur : https://linkinghub.elsevier.com/retrieve/pii/S0959804921012624

2021

LIVERMETSURVEY / Giuliante F, Viganò L, De Rose AM, Mirza DF, Lapointe R, Kaiser G, Barroso E, Ferrero A, Isoniemi H, Lopez-Ben S, Popescu I, Ouellet JF, Hubert C, Regimbeau JM, Lin JK, Skipenko OG, Ardito F, Adam R. Liver-First Approach for Synchronous Colorectal Metastases: Analysis of 7360 Patients from the LiverMetSurvey Registry Ann Surg Oncol 2021 Dec ; 28(13):8198-8208
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/34212254/

COLORECTAL / Goldberg RM, Adams R, Buyse M, Eng C, Grothey A, Andre T, Sobrero AF, Lichtman SM, Benson AB, Punt CJA, Maughan T, Burzykowski T, Sommeijer D, Saad ED, Shi Q, Coart E, Chibaudel B, Koopman M, Schmoll HJ, Yoshino T, Taieb J, Tebbutt NC, Zalcberg J, Tabernero J, Van Cutsem E, Matheson A, de Gramont A. Clinical Trial Endpoints in Metastatic Cancer: Using Individual Participant Data to Inform Future Trials Methodology. J Natl Cancer Inst. 2021 Dec 4 PMID: 34865086 DOI: 10.1093/jnci/djab218
Disponible sur : https://academic.oup.com/jnci/article-abstract/114/6/819/6449449?redirectedFrom=fulltext&login=false

COLORECTAL / Yin J, Dawood S, Cohen R, Meyers J, Zalcberg J, Yoshino T, Seymour M, Maughan T, Saltz L, Van Cutsem E, Venook A, Schmoll HJ, Goldberg R, Hoff P, Hecht JR, Hurwitz H, Punt C, Diaz Rubio E, Koopman M, Cremolini C, Heinemann V, Tournigard C, Bokemeyer C, Fuchs C, Tebbutt N, Souglakos J, Doulliard JY, Kabbinavar F, Chibaudel B, de Gramont A, Shi Q, Grothey A, Adams R.  Impact of geography on prognostic outcomes of 21,509 patients with metastatic colorectal cancer enrolled in clinical trials: an ARCAD database analysis. Ther Adv Med Oncol. 2021 ; 13:17588359211020547 PMID: 34262614 PMCID: 8252342 DOI: 10.1177/17588359211020547
Disponible sur : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252342/

COLORECTAL / Yin J, Cohen R, Jin Z, Liu H, Pederson L, Adams R, Grothey A, Maughan TS, Venook A, Van Cutsem E, Punt C, Koopman M, Falcone A, Tebbutt NC, Seymour MT, Bokemeyer C, Rubio ED, Kaplan R, Heinemann V, Chibaudel B, Yoshino T, Zalcberg J, Andre T, De Gramont A, Shi Q, Lenz HJ. Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer. J Natl Cancer Inst. 2021 Jun 1 PMID: 34061178 DOI: 0.1093/jnci/djab112
Disponible sur : https://academic.oup.com/jnci/article/113/12/1705/6290718?login=false

COLORECTAL / Cohen R, Liu H, Fiskum J, Adams R, Chibaudel B, Maughan TS, Van Cutsem E, Venook A, Douillard JY, Heinemann V, Punt CJA, Falcone A, Bokemeyer C, Kaplan R, Lenz HJ, Koopman M, Yoshino T, Zalcberg J, Grothey A, de Gramont A, Shi Q, Andre T.  BRAF V600E Mutation in First-line Metastatic Colorectal Cancer: an Analysis of Individual Patient Data from the ARCAD Database. J Natl Cancer Inst. 2021 Mar 18 PMID: 33734401 DOI: 10.1093/jnci/djab042
Disponible sur : https://academic.oup.com/jnci/article/113/10/1386/6178005?login=false

2020

COLORECTAL / Lopes GS, Tournigand C, Olswold CL, Cohen R, Kempf E, Saltz L, Goldberg RM, Hurwitz H, Fuchs C, de Gramont A, Shi Q.  Adverse event load, onset, and maximum grade: A novel method of reporting adverse events in cancer clinical trials. Clin Trials. 2020 Oct 1 ; 1740774520959313 PMID: 32998522 DOI: 10.1177/1740774520959313
Disponible sur : https://journals.sagepub.com/doi/10.1177/1740774520959313

COLORECTAL / Gulhati P, Yin J, Pederson L, Schmoll HJ, Hoff P, Douillard JY, Hecht JR, Tournigand C, Tebbut N, Chibaudel B, De Gramont A, Shi Q, Overman MJ.  Threshold Change in CEA as a Predictor of Non-Progression to First-Line Systemic Therapy in Metastatic Colorectal Cancer Patients with Elevated CEA. J Natl Cancer Inst. 2020 Mar 19 [Epub ahead of print] PMID: 32191317 DOI: 10.1093/jnci/djaa020
Disponible sur : https://academic.oup.com/jnci/article/112/11/1127/5810087?login=false

2019

COLORECTAL / Burzykowski T, Coart E, Saad ED, Shi Q, Sommeijer DW, Bokemeyer C, Diaz-Rubio E, Douillard JY, Falcone A, Fuchs CS, Goldberg RM, Hecht JR, Hoff PM, Hurwitz H, Kabbinavar FF, Koopman M, Maughan TS, Punt CJA, Saltz L, Schmoll HJ, Seymour MT, Tebbutt NC, Tournigand C, Van Cutsem E, de Gramont A, Zalcberg JR, Buyse M, Aide et Recherche en Cancerologie Digestive Group.  Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer. JAMA Netw Open. 2019 Sep 4; 2 (9):e1911750 PMID: 31539075 DOI: 10.1001/jamanetworkopen.2019.11750
Disponible sur : https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2751555

2018

COLORECTAL / Salem ME, Yin J, Weinberg BA, Renfro LA, Pederson LD, Maughan TS, Adams RA, Van Cutsem E, Falcone A, Tebbutt NC, Seymour MT, Diaz-Rubio E, Aranda E, Bokemeyer C, Heinemann V, Wasan H, de Gramont A, Grothey A, Shi Q, Sargent DJ, Marshall JL.  Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database. Eur J Cancer. 2018 Nov ; 103:205-213 PMID: 30268921 DOI: 10.1016/j.ejca.2018.08.020
Disponible sur : https://www.ejcancer.com/article/S0959-8049(18)31340-6/abstract

COLORECTAL / Goey KKH, Sorbye H, Glimelius B, Adams RA, Andre T, Arnold D, Berlin JD, Bodoky G, de Gramont A, Diaz-Rubio E, Eng C, Falcone A, Grothey A, Heinemann V, Hochster HS, Kaplan RS, Kopetz S, Labianca R, Lieu CH, Meropol NJ, Price TJ, Schilsky RL, Schmoll HJ, Shacham-Shmueli E, Shi Q, Sobrero AF, Souglakos J, Van Cutsem E, Zalcberg J, van Oijen MGH, Punt CJA, Koopman M.  Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group. Eur J Cancer. 2018 Sep; 100:35-45 PMID: 29936065 DOI: 10.1016/j.ejca.2018.05.010
Disponible sur : https://www.ejcancer.com/article/S0959-8049(18)30850-5/abstract

COLORECTAL / Sjoquist KM, Renfro LA, Simes RJ, Tebbutt NC, Clarke S, Seymour MT, Adams R, Maughan TS, Saltz L, Goldberg RM, Schmoll HJ, Van Cutsem E, Douillard JY, Hoff PM, Hecht JR, Tournigand C, Punt CJA, Koopman M, Hurwitz H, Heinemann V, Falcone A, Porschen R, Fuchs C, Diaz-Rubio E, Aranda E, Bokemeyer C, Souglakos I, Kabbinavar FF, Chibaudel B, Meyers JP, Sargent DJ, de Gramont A, Zalcberg JR, Fondation Aide et Recherche en Cancerologie Digestive Group.  Personalizing Survival Predictions in Advanced Colorectal Cancer: The ARCAD Nomogram Project. J Natl Cancer Inst. 2018 June; 110 (6):638-648 PMID: 29267900 DOI: 10.1093/jnci/djx253
Disponible sur : https://academic.oup.com/jnci/article/110/6/638/4757465?login=false

COLORECTAL / van Rooijen KL, Shi Q, Goey KKH, Meyers J, Heinemann V, Diaz-Rubio E, Aranda E, Falcone A, Green E, de Gramont A, Sargent DJ, Punt CJA, Koopman M. Prognostic value of primary tumour resection in synchronous metastatic colorectal cancer: Individual patient data analysis of first-line randomised trials from the ARCAD database. Eur J Cancer. 2018 Jan 17; 91:99-106 [Epub ahead of print] PMID: 29353165 DOI: 10.1016/j.ejca.2017.12.014
Disponible sur : https://linkinghub.elsevier.com/retrieve/pii/S0959804917314934

2017

LIVERMETSURVEY / Hosokawa I, Allard MA, Mirza DF, Kaiser G, Barroso E, Lapointe R, Laurent C, Ferrero A, Miyazaki M and Adam R. Outcomes of parenchyma-preserving hepatectomy and right hepatectomy for solitary small colorectal liver metastasis: A LiverMetSurvey study. Surgery. 2017, 162(2): 223-232.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/28434557/

LIVERMETSURVEY / Allard MA, Adam R, Giuliante F, Lapointe R, Hubert C, Ijzermans JNM, Mirza DF, Elias D, Laurent C, Gruenberger T, Poston G, Letoublon C, Isoniemi H, Lucidi V, Popescu I and Figueras J. Long-term outcomes of patients with 10 or more colorectal liver metastases. Br J Cancer. 2017, 117(5): 604-611.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/28728167/

COLORECTAL / Bleiberg H, Decoster G, de Gramont A, Rougier P, Sobrero A, Benson A, Chibaudel B, Douillard JY, Eng C, Fuchs C, Fujii M, Labianca R, Larsen AK, Mithchell E, Schmool HJ, Sprumont D, Zalcberg J. A need to simplify informed consent documents in cancer clinical trials. A position paper of the ARCAD group. Annals of Oncology 0:922-930, 2017 doi:10.1093/annonc/mdx050
Disponible sur : https://linkinghub.elsevier.com/retrieve/pii/S092375341932023X

LIVERMETSURVEY / Adam R, Yi B, Innominato PF, Barroso E, Laurent C, Giuliante F, Capussotti L, Lapointe R, Regimbeau JM, Lopez-Ben S, Isoniemi H, Hubert C, Lin JK, Gruenberger T, Elias D, Skipenko OG and Guglielmi A. Resection of colorectal liver metastases after second-line chemotherapy: is it worthwhile? A LiverMetSurvey analysis of 6415 patients. Eur J Cancer. 2017, 78(7-15.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/28407529/

COLORECTAL / Bonnetain F, Borg C, Adams RR, Ajani JA, Benson A, Bleiberg H, Chibaudel B, Diaz-Rubio E, Douillard JY, Fuchs CS, Giantonio BJ, Goldberg R, Heinemann V, Koopman M, Labianca R, Larsen AK, Maughan T, Mitchell E, Peeters M, Punt CJA, Schmoll HJ, Tournigand C, de Gramont A. How health-related quality of life assessment should be used in advanced colorectal cancer clinical trials. Ann Oncol. 2017 Apr 18
Disponible sur : https://linkinghub.elsevier.com/retrieve/pii/S0923753419352287

COLORECTAL / ARCAD Clinical Trials Program, Renfro LA, Goldberg RM, Grothey A, Sobrero A, Adams R, Seymour MT, Heinemann V, Schmoll HJ, Douillard JY, Hurwitz H, Fuchs CS, Diaz-Rubio E, Porschen R, Tournigand C, Chibaudel B, Hoff PM, Kabbinavar FF, Falcone A, Tebbutt NC, Punt CJA, Hecht JR, Souglakos J, Bokemeyer C, Van Cutsem E, Saltz L, de Gramont A, Sargent DJ. Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancerologie Digestive Database. J Clin Oncol 2017 Jun 10; 35 (17):1929-1937 PMID:28414610 DOI:10.1200/JCO.2016.71.5771
Disponible sur : https://ascopubs.org/doi/10.1200/JCO.2016.71.5771

LIVERMETSURVEY / Regimbeau JM, Cosse C, Kaiser G, Hubert C, Laurent C, Lapointe R, Isoniemi H and Adam R. Feasibility, safety and efficacy of two-stage hepatectomy for bilobar liver metastases of colorectal cancer: a LiverMetSurvey analysis. HPB (Oxford). 2017, 19(5): 396-405.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/28343889/

2016

COLORECTAL / Franko J, Shi Q, Meyers JP, Maughan TS, Adams RA, Seymour MT, Saltz L, Punt CJA, Koopman M, Tournigand C, Tebbutt NC, Diaz-Rubio E, Souglakos J, Falcone Alfredo, Chibaudel B, Heinemann V, Moen J, De Gramount Aimery, Sargent DJ, Grothey A, for the Analysis and Research in Cancers of the Digestive System (ARCAD) group. Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomized trials from the analysis and research in cancers of the digestive system (ARCAD) database. Lancet Oncol 2016 Dec; 17 (12):1709-1719 PMID: 27743922 DOI: 10.1016/S1470-2045(16)30500-9.
Disponible sur : https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(16)30500-9/abstract

COLORECTAL / Renfro LA, Loupakis F, Adams RA, Seymour MT, Heinemann V, Schmoll HJ, Douillard JY, Hurwitz H, Fuchs CS, Diaz-Rubio E, Porschen R, Tournigand C, Chibaudel B, Falcone A, Tebbutt NC, Punt CJ, Hecht JR, Bokemeyer C, Van Cutsem E, Goldberg RM, Saltz LB, de Gramont A, Sargent DJ, Lenz HJ. Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database. J Clin Oncol. 2016 Jan 10;34(2):144-50. doi: 10.1200/JCO.2015.61.6441. Epub 2015 Oct 26.  PMID:  26503203
Disponible sur : https://ascopubs.org/doi/10.1200/JCO.2015.61.6441

2015

COLORECTAL / de Gramont A, Watson S, Ellis LM, Rodón J, Tabernero J,  de Gramont  A, Hamilton SR. Pragmatic issues in biomarker evaluation for targeted therapies in cancer. Nature Reviews Clinical Oncology 2015 ; 12:197–212 doi:10.1038/nrclinonc.2014.202
Disponible sur : https://www.nature.com/articles/nrclinonc.2014.202

LIVERMETSURVEY / Adam R, de Gramont A, Figueras J, Kokudo N, Kunstlinger F, Loyer E, Poston G, Rougier P, Rubbia-Brandt L, Sobrero A, Teh C, Tejpar S, Van Cutsem E, Vauthey JN, Påhlman L; of the EGOSLIM (Expert Group on OncoSurgery management of LIver Metastases) Managing synchronous liver metastases from colorectal cancer: A multidisciplinary international consensus. Cancer Treat Rev. 2015 Nov ; 41(9):729-41.341.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/26417845/

LIVERMETSURVEY / Bonney GK, Coldham C, Adam R, Kaiser G, Barroso E, Capussotti L, Laurent C, Verhoef C, Nuzzo G, Elias D, Lapointe R, Hubert C, Lopez-Ben S, Krawczyk M, Mirza DF; LiverMetSurvey International Registry Working Role of neoadjuvant chemotherapy in resectable synchronous colorectal liver metastasis; An international multi-center data analysis using LiverMetSurvey. J Surg Oncol. 2015 May ; 111(6):716-24.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/25864987/

LIVERMETSURVEY / Andres A, Mentha G, Adam R, Gerstel E, Skipenko OG, Barroso E, Lopez-Ben S, Hubert C, Majno PE, Toso Surgical management of patients with colorectal cancer and simultaneous liver and lung metastases. Br J Surg. 2015 May ; 102(6):691-9.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/25789941/

2014

COLORECTAL / Shi Q, De Gramont A, Grothey A, Zalcberg J, Chibaudel B, Schmoll HJ, Seymour MT, Adams RA, Saltz L, Goldberg RM, Punt CJA, Douillard JY, Hoff PM, Hecht JR, Hurwitz H, Diaz-Rubio E, Porschen R, Tebbutt NC, Fuchs CS, Souglakos J, Falcone A, Tournigand C, Kabbinavar FF, Heinemann V, Van Cutsem E, Bokemeyer C, Buyse ME, Sargent DJ. Individual patient data analysis of progression-free survival versus overall survival as a first-line end point for metastatic colorectal cancer in modern randomized trials: Findings from the analysis and research in cancers of the digestive system database. J Clin Oncol. 2014 Nov 10. DOI: 10.1200/JCO.2014.56.5887
Disponible sur : https://ascopubs.org/doi/10.1200/JCO.2014.56.5887

LIVERMETSURVEY / Parkin E, O’Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D, Capussotti L, Renehan AG; LiverMetSurvey Equivalent survival in patients with and without steatosis undergoing resection for colorectal liver metastases following pre-operative chemotherapy. Eur J Surg Oncol. 2014 Nov;40(11):1436-44.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/25189474/

LIVERMETSURVEY / Jegatheeswaran S, Jamdar S, Satyadas T, Sheen AJ, Adam R, Siriwardena AK. Use of Pharmacologic Agents for Modulation of Ischaemia-Reperfusion Injury after Hepatectomy: A Questionnaire Study of the LiverMetSurvey International Registry of Hepatic Surgery HPB Surg. 2014;2014:437159.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/25477707/

COLORECTAL / Lieu C, Renfro LA, de Gramont A, Maughan TS, Seymour MT, Saltz L, Goldberg RM, Sargent DJ, Eckhardt SG, Eng C. Association of age with survival in patients with metastatic colorectal cancer: analysis from the ARCAD clinical trials program. J Clin Oncol.  2014 Sep 20;32(27):2975-2982. DOI: 10.1200/JCO.2013.54.9329
Disponible sur : https://ascopubs.org/doi/10.1200/JCO.2013.54.9329

LIVERMETSURVEY / Rong Z, Martel G, Vandenbroucke-Menu F, Adam R, Lapointe Impact of peri-operative bevacizumab on survival in patients with resected colorectal liver metastases: an analysis of the LiverMetSurvey. HPB (Oxford). 2014 Apr;16(4):342-9.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/24641317/

LIVERMETSURVEY / Viganò L, Capussotti L, Lapointe R, Barroso E, Hubert C, Giuliante F, Ijzermans JN, Mirza DF, Elias D, Adam R. Early recurrence after liver resection for colorectal metastases: risk factors, prognosis, and A LiverMetSurvey-based study of 6,025 patients. Ann Surg Oncol. 2014 Apr;21(4):1276-86.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/24346766/

2013

LIVERMETSURVEY / Parkin E, O’Reilly DA, Adam R, Kaiser GM, Laurent C, Elias D, Capussotti L, Renehan AG; LiverMetSurvey The effect of hepatic steatosis on survival following resection of colorectal liver metastases in patients without preoperative chemotherapy. HPB (Oxford). 2013 Jun;15(6):463- 72.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/23458109/

2012

LIVERMETSURVEY / Andres A, Toso C, Adam R, Barroso E, Hubert C, Capussotti L, Gerstel E, Roth A, Majno PE, Mentha G. A survival analysis of the liver-first reversed management of advanced simultaneous colorectal liver metastases: a LiverMetSurvey-based Annals of Surgery. 2012 Nov;256(5):772-8; discussion 778- 9.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/23095621/

LIVERMETSURVEY / Viganò L, Capussotti L, Barroso E, Nuzzo G, Laurent C, Ijzermans JN, Gigot JF, Figueras J, Gruenberger T, Mirza DF, Elias D, Poston G, Letoublon C, Isoniemi H, Herrera J, Sousa FC, Pardo F, Lucidi V, Popescu I, Adam R. Progression while receiving preoperative chemotherapy should not be an absolute contraindication to liver resection for colorectal Annals of Surgical Oncology. 2012 Sep;19(9):2786-96.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/22622469/

LIVERMETSURVEY / Adam R, De Gramont A, Figueras J, Guthrie A, Kokudo N, Kunstlinger F, Loyer E, Poston G, Rougier P, Rubbia-Brandt L, Sobrero A, Tabernero J, Teh C, Van Cutsem E; Jean-Nicolas Vauthey of the EGOSLIM (Expert Group on OncoSurgery management of LIver Metastases) The oncosurgery approach to managing liver metastases from colorectal cancer: a multidisciplinary international consensus. Oncologist. 2012;17(10):1225-39.
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/22962059/

COLORECTAL / Sargent DJ, Buyse M, Matheson A, Goldberg RM, de Gramont, ARCAD Clinical. The ARCAD clinical trials program: an update and invitation.  Oncologist. 2012; 17(2):188-91. PMID:22302228. PMCID:3286167. DOI:10.1634/theoncologist.2011-0332.
Disponible sur : https://academic.oup.com/oncolo/article/17/2/188/6403318?login=false

2011

COLORECTAL / Buyse M, Michiels S, Sargent DJ, Grothey A,  Matheson A & de Gramont A. Integrating biomarkers in clinical trials. Expert Rev. 2011;11(2): 171–182
Disponible sur : https://www.tandfonline.com/doi/full/10.1586/erm.10.120

COLORECTAL / Chibaudel B, Bonnetain F, Shi Q, Buyse M, Tournigand C, Sargent DJ, Allegra CJ, Goldberg RM, de Gramont A. Alternative end points to evaluate a therapeutic strategy in advanced colorectal cancer: evaluation of progression-free survival, duration of disease control, and time to failure of strategy–an Aide et Recherche en Cancerologie Digestive Group Study.  J Clin Oncol. 2011 Nov 1 ; 29(31):4199-204 ; PMID:21969501. DOI:10.1200/JCO.2011.35.5867.
Disponible sur : https://ascopubs.org/doi/10.1200/JCO.2011.35.5867

LIVERMETSURVEY / Adam R, Barroso E, Laurent C, Nuzzo G, Hubert C, Mentha G, Ijzermans J, Capussotti L, Lopezben S, Mirza D, Kaiser G, Oussoultzoglou E, Gruenberger T, Poston GJ, Skipenko O, Centers Impact of the type and modalities of preoperative chemotherapy on the outcome of liver resection for colorectal metastases. Journal of Clinical Oncology 2011 ; 29 (15 Suppl May): 3519
Disponible sur : https://ascopubs.org/doi/10.1200/jco.2011.29.15_suppl.3519

2010

COLORECTAL / Buyse M, Sargent DJ, Grothey A, Matheson A, de Gramont A. Biomarkers and surrogate end points – the challenge of statistical validation.  Nature Reviews Clinical Oncology 2010; 7:309-317. doi:10.1038/nrclinonc.2010.43
Disponible sur : https://www.nature.com/articles/nrclinonc.2010.43

LIVERMETSURVEY / Adam R, Bhangui P, Poston G, Mirza D, Nuzzo G, Barroso E, Ijzermans J, Hubert C, Ruers T, Capussotti L, Ouellet JF, Laurent C, Cugat E, Colombo PE, Milicevic Is perioperative chemotherapy useful for solitary, metachronous, colorectal liver metastases? Annals of Surgery. 2010 Nov ; 252(5):774- 87
Disponible sur : https://pubmed.ncbi.nlm.nih.gov/21037433/

COLORECTAL / de Gramont, Haller DG, Sargent DJ, Tabernero J, Matheson A, Schilsky RL. Toward efficient trials in colorectal cancer: the ARCAD Clinical Trials Program. J Clin Oncol. 2010 Feb 1; 28(4):527-30. PMID:19841311. DOI:10.1200/JCO.2009.25.2544.
Disponible sur : https://ascopubs.org/doi/10.1200/JCO.2009.25.2544

LIVERMETSURVEY / Adam R, Frilling A, Elias D, Laurent C, Figueras J, Capussotti L, Poston GJ, Wicherts DA, de Haas Liver resection of colorectal metastases in elderly patients. British Journal of Surgery 2010 ; 97(3):366-
Disponible sur : https://doi.org/10.1002/bjs.6889